In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A.
نویسندگان
چکیده
We evaluated a novel truncated hygromycin A analog in which the furanose ring was replaced with a 2-fluoro-2-cyclopropylethyl substituent for its activity against multidrug resistant gram-positive bacteria and compared its activity to the activities of linezolid, quinupristin-dalfopristin, and vancomycin. CE-156811 demonstrated robust in vitro activity against gram-positive bacteria that was comparable to that of linezolid.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 52 7 شماره
صفحات -
تاریخ انتشار 2008